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Topology and Physics of Circular DNA (1992)

Topology and Physics of Circular DNA (1992) PDF Author: Alexander Vologodskii
Publisher: CRC Press
ISBN: 1351355821
Category : Medical
Languages : en
Pages : 246

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Book Description
Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

Topology and Physics of Circular DNA (1992)

Topology and Physics of Circular DNA (1992) PDF Author: Alexander Vologodskii
Publisher: CRC Press
ISBN: 1351355821
Category : Medical
Languages : en
Pages : 246

View

Book Description
Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

Topology and Physics of Circular DNA (1992)

Topology and Physics of Circular DNA (1992) PDF Author: Alexander Vologodskii
Publisher: CRC Press
ISBN: 135135583X
Category : Medical
Languages : en
Pages : 192

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Book Description
Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :

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Atomic Force Microscopy in Cell Biology

Atomic Force Microscopy in Cell Biology PDF Author:
Publisher: Academic Press
ISBN: 0080549446
Category : Science
Languages : en
Pages : 415

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Book Description
This is the first book to cover the history, structure, and application of atomic force microscopy in cell biology. Presented in the clear, well-illustrated style of the Methods in Cell Biology series, it introduces the AFM to its readers and enables them to tap the power and scope of this technology to further their own research. A practical laboratory guide for use of the atomic force and photonic force microscopes, it provides updated technology and methods in force spectroscopy. It is also a comprehensive and easy-to-follow practical laboratory guide for the use of the AFM and PFM in biological research.

Giant Molecules

Giant Molecules PDF Author:
Publisher:
ISBN: 9814468606
Category :
Languages : en
Pages :

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Current Catalog

Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :

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Book Description
First multi-year cumulation covers six years: 1965-70.

Cyclic Polymers

Cyclic Polymers PDF Author: E.R. Semlyen
Publisher: Springer Science & Business Media
ISBN: 0306471175
Category : Technology & Engineering
Languages : en
Pages : 790

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Book Description
Cyclic Polymers (Second Edition) reviews the many recent advances in this rapidly expanding subject since the publication of the first edition in 1986. The preparation, characterisation, properties and applications of a wide range of organic and inorganic cyclic oligomers and polymers are described in detail, together with many examples of catenanes and rotaxanes. The importance of large cyclics in biological chemistry and molecular biology is emphasised by a wide coverage of circular DNA, cyclic peptides and cyclic oligosaccharides and polysaccharides. Experimental techniques and theoretical aspects of cyclic polymers are included, as well as examples of their uses such as ring opening polymerisation reactions to give commercially important materials. This book covers a wide range of topics which should be of interest to many scientific research workers (for example, in polymer science, chemistry and molecular biology), as well as providing a reference text for undergraduate and graduate students.

New Trends in Geometry

New Trends in Geometry PDF Author: Luciano Boi
Publisher: World Scientific
ISBN: 1848166435
Category : Mathematics
Languages : en
Pages : 329

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Book Description
This volume focuses on the interactions between mathematics, physics, biology and neuroscience by exploring new geometrical and topological modelling in these fields. Among the highlights are the central roles played by multilevel and scale-change approaches in these disciplines. The integration of mathematics with physics, as well as molecular and cell biology and the neurosciences, will constitute the new frontier of 21st century science, where breakthroughs are more likely to span across traditional disciplines.

Links Between Recombination and Replication

Links Between Recombination and Replication PDF Author: Proceedings of the National Academy of Sciences
Publisher: National Academies Press
ISBN: 030907424X
Category : Electronic book
Languages : en
Pages : 303

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Book Description
There has been a sea change in how we view genetic recombination. When germ cells are produced in higher organisms, genetic recombination assures the proper segregation of like chromosomes. In the course of that process, called meiosis, recombination not only assures segregation of one chromosome of each type to progeny germ cells, but also further shuffles the genetic deck, contributing to the unique inheritance of individuals. In a nutshell, that is the classical view of recombination. We have also known for many years that in bacteria recombination plays a role in horizontal gene transfer and in replication itself, the latter by establishing some of the replication forks that are the structural scaffolds for copying DNA. In recent years, however, we have become increasingly aware that replication, which normally starts without any help from recombination, is a vulnerable process that frequently leads to broken DNA. The enzymes of recombination play a vital role in the repair of those breaks. The recombination enzymes can function via several different pathways that mediate the repair of breaks, as well as restoration of replication forks that are stalled by other kinds of damage to DNA. Thus, to the classical view of recombination as an engine of inheritance we must add the view of recombination as a vital housekeeping function that repairs breaks suffered in the course of replication. We have also known for many years that genomic instability--including mutations, chromosomal rearrangements, and aneuploidy--is a hallmark of cancer cells. Although genomic instability has many contributing causes, including faulty replication, there are many indications that recombination, faulty or not, contributes to genome instability and cancer as well. The (Nas colloquium) Links Between Recombination and Replication: Vital Roles of Recombination was convened to broaden awareness of this evolving area of research. Papers generated by this colloquium are published here. To encourage the desired interactions of specialists, we invited some contributions that deal only with recombination or replication in addition to contributions on the central thesis of functional links between recombination and replication. To aid the nonspecialist and specialist alike, we open the set of papers with a historical overview by Michael Cox and we close the set with a commentary on the meeting and the field by Andrei Kuzminov.

Cyclic Polymers

Cyclic Polymers PDF Author: J. A. Semlyen
Publisher: Springer Science & Business Media
ISBN: 0412830906
Category : Science
Languages : en
Pages : 804

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Book Description
Cyclic Polymers (Second Edition) reviews the many recent advances in this rapidly expanding subject since the publication of the first edition in 1986. The preparation, characterisation, properties and applications of a wide range of organic and inorganic cyclic oligomers and polymers are described in detail, together with many examples of catenanes and rotaxanes. The importance of large cyclics in biological chemistry and molecular biology is emphasised by a wide coverage of circular DNA, cyclic peptides and cyclic oligosaccharides and polysaccharides. Experimental techniques and theoretical aspects of cyclic polymers are included, as well as examples of their uses such as ring opening polymerisation reactions to give commercially important materials. This book covers a wide range of topics which should be of interest to many scientific research workers (for example, in polymer science, chemistry and molecular biology), as well as providing a reference text for undergraduate and graduate students.