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New Trends in the Molecular and Biological Basis for Clinical Oncology

New Trends in the Molecular and Biological Basis for Clinical Oncology PDF Author: Tetsuhiko Tachikawa
Publisher: Springer Science & Business Media
ISBN: 443188663X
Category : Medical
Languages : en
Pages : 192

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Book Description
Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.

New Trends in the Molecular and Biological Basis for Clinical Oncology

New Trends in the Molecular and Biological Basis for Clinical Oncology PDF Author: Tetsuhiko Tachikawa
Publisher: Springer Science & Business Media
ISBN: 443188663X
Category : Medical
Languages : en
Pages : 192

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Book Description
Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.

New Trends in the Molecular and Biological Basis for Clinical Oncology

New Trends in the Molecular and Biological Basis for Clinical Oncology PDF Author: Tetsuhiko Tachikawa
Publisher: Springer
ISBN: 9784431998648
Category : Medical
Languages : en
Pages : 192

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Book Description
Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.

Human Gene Therapy: Current Opportunities and Future Trends

Human Gene Therapy: Current Opportunities and Future Trends PDF Author: G. M. Rubanyi
Publisher: Springer Science & Business Media
ISBN: 9783540004134
Category : Medical
Languages : en
Pages : 276

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Book Description
Advances in genetics, molecular biology and gene delivery technologies in recent years have led to new gene therapy strategies for treatment of a variety of diseases. This book gives a comprehensive overview of the present status and future directions of gene delivery systems and therapeutic strategies for the clinical application of gene therapy in cancer, cardiovascular and central nervous system diseases. Stem cell-based therapies and gene expression regulatory systems as novel platform technologies for various gene therapy applications are also discussed. Leading experts give excellent overviews of basic molecular aspects and clinical applications in this new emerging biomedical field.

Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs

Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs PDF Author: Sundas Fayyaz
Publisher: Springer
ISBN: 3319715534
Category : Medical
Languages : en
Pages : 308

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Book Description
Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics. This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.

The Molecular Basis of Human Cancer

The Molecular Basis of Human Cancer PDF Author: William B. Coleman
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 610

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Book Description
The Molecular Basis of Human Cancer covers general molecular concepts in neoplastic transformation, state of the art, detailed descriptions of molecular mechanisms in specific human cancers, and rapidly evolving aspects of cancer research and treatment that are based on molecular mechanisms. Also included is coverage of future issues in human cancer research and treatment, including genetic counseling, molecular diagnosis, molecular pharmacology, and gene therapy. This volume provides an excellent background for the novice on general concepts and established principles governing human neoplastic transformation and tumorigenesis. It also supplies detailed information in organ-specific cancers for the more advanced reader. In addition, the book includes excellent coverage of various topics related to current trends in cancer research and treatment, providing the reader with insight into cutting edge aspects of the cancer field.

Lung Cancer Metastasis

Lung Cancer Metastasis PDF Author: Venkateshwar Keshamouni
Publisher: Springer
ISBN: 9781441907714
Category : Medical
Languages : en
Pages : 409

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Book Description
Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collaboration and foster much needed translational research; and b) to introduce new and emerging concepts and approaches in metastasis research to lung cancer research community at large. In this attempt, the book will cover a broad spectrum of subjects ranging from the current trends in the clinical management of the metastatic disease, to the systems biology approach for gaining insights into the mechanisms of metastasis. Some of the subjects covered will include: defining basic hallmarks of a metastatic cell, the concept of tumor stem cells, epithelial-mesenchymal transitions, evasion of immune-surveillance, tumor-stromal interactions, angiogenesis, molecular imaging and biomarker discovery.

Translational Research in Breast Cancer

Translational Research in Breast Cancer PDF Author: Erwei Song
Publisher: Springer
ISBN: 9789811060199
Category : Medical
Languages : en
Pages : 418

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Book Description
This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer. With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the immuno-environment has been demonstrated as the barrier to clinical cancer. In addition, major advances in cancer biology, immunology, genomics and metabolism have broken new ground for designing therapeutic approaches and selecting appropriate treatments on the basis of more precise information on the individual patient. As a result of these two trends, a clearer picture of the molecular landscape of breast cancers has facilitated the development of diagnostic, prognostic and predictive biomarkers for clinical oncology. All these aspects are addressed in this volume, which offers a comprehensive resource for researchers, graduate students and oncologists in cancer research.

List of Journals Indexed in Index Medicus

List of Journals Indexed in Index Medicus PDF Author:
Publisher:
ISBN:
Category : Index medicus (National Library of Medicine (U.S.))
Languages : en
Pages : 308

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Book Description
Issues for 1977-1979 include also Special list journals being indexed in cooperation with other institutions. Citations from these journals appear in other MEDLARS bibliographies and in MEDLINE, but not in Index medicus.

Contemporary Issues in Lymphoma

Contemporary Issues in Lymphoma PDF Author: Mary Ellen McFadden
Publisher: Jones & Bartlett Learning
ISBN: 9780763729578
Category : Medical
Languages : en
Pages : 288

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Book Description
Understanding the nuances associated with the various neoplasm's that comprise lymphomas can be a challenge to nursing professionals. This book helps broaden the awareness of the biology, classification, and treatment options available to patients with lymphoma. Contemporary Issues in Lymphoma provides an overview of lymphoid malignancies (including epidemiology and etiology), the immune system and lymphoid malignancies, and the cytogenetics of lymphoid malignancies.

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1994

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1994 PDF Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher:
ISBN:
Category : United States
Languages : en
Pages :

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Book Description